The Chi-squared test followed closely by multivariate logistic regression were used to determine the factors from the occurrence of CED. Our information suggested that 32% associated with expecting mothers had CED. Univariate analysis unearthed that maternal age (p=0.022), maternity interval (p=0.009), academic attainment (p=0.012), understanding of nourishment and CED (p=0.023), regularity of utilization of ANC services (p=0.028), power intake (p=0.002), protein consumption (p=0.006), vitamin C intake (p=0.016), folate intake (p=0.011), and calcium intake (p=0.004) had been notably involving CED occurrence into the pregnant women. Multivariate analysis suggested that extreme maternal age (OR; 3.49; 95%CI 1.10-11.05), low educational attainment (OR 4.12; 95%Cwe 1.37-12.33), brief pregnancy period (OR; 7.30; 95%CI 1.84-28.99), low-frequency of ANC (OR 3.06; 95%Cwe 1.01-9.19) and reduced protein intake (OR 6.80; 95%Cwe 1.62-28.59) were related to CED occurrence. This research underscores the necessity of increasing health consumption, regularity of ANC, and maternity interval among pregnant women to reduce the risk of CED and its own unpleasant health outcomes.Mitral stenosis is one of common rheumatic heart disease (RHD) disorder worldwide, including in Indonesia. This pathological condition causes kept atrial pressure, leading to left atrial fibrosis that impacts the structure and function of the left atrial as well as the clinical condition. The aim of this research was to assess the correlation between circulating fibrosis biomarkers with net atrioventricular compliance (Cn) as a parameter of left atrial function, and left atrial amount index (LAVI) as a parameter left atrium construction of changes. A cross-sectional research ended up being conducted at Panti Rahayu Hospital and Permata Bunda Hospital, Purwodadi, Central Java, with a complete of 40 RHD customers with serious mitral stenosis. The ELISA ended up being utilized to measure the levels of carboxy-terminal propeptide of kind I procollagen (PICP), matrix metalloproteinase I (MMP-1), tissue inhibitor matrix metalloproteinase 1 (TIMP-1), and changing growth factor-β1 (TGF-β1). The left atrial purpose ended up being examined by calculating Cn, while the LAVI variables were calculated to assess remaining atrium structure/size. The mean levels of circulating fibrosis biomarkers were as follows PICP 153.96±89.12 ng/mL; MMP-1 1.44±2.12 ng/mL; MMP-1/TIMP-1 ratio 0.38±0.54 and TGF-β1 2.66±1.96 pg/mL. From the echocardiographic analysis, the mean Cn was check details 5.24±1.93 mL/mmHg additionally the mean LAVI ended up being 152.55±79.36 mL/m2. There were significant correlation between MMP-1 and MMP-1/TIMP-1 ratio with Cn (r=0.345 and r=0.333, correspondingly; both had p0.05). This study highlights that MMP-1 and MMP-1/TIMP-1 ratio are potentially to be used as markers to look for the Cn in RHD patients with severe mitral stenosis. But, further studies with an increased sample size are essential to ensure this finding.Persistent symptoms following the coronavirus disease 2019 (COVID-19, referred to as post-COVID syndrome (PCS), provided psycho oncology a continuous health burden among COVID-19 survivors, including wellness workers. The existence of weakness in mild COVID-19 survivors has not been commonly reported. The purpose of this study would be to provide the observable symptoms of tiredness in medical employees which practiced mild COVID-19 additionally the elements associated with exhaustion. A cross-sectional research was conducted at H. Adam Malik General Hospital in Medan, Indonesia, from September to December 2022, included physicians, nurses, supplementary workers, and medical assistance workers whom experienced mild COVID-19. Weakness was calculated by a fatigue assessment scale (FAS). The considered possible risk facets had been sex, age, vaccination record, comorbid, existence of PCS, length of time of PCS symptoms, and wide range of PCS symptoms. The Chi-squared or Fisher’s precise tests were used to evaluate the association between the incidence of exhaustion and risk factors. An overall total of 100 health care wort exhaustion.Budd-Chiari problem is just one of the post-hepatic factors behind portal high blood pressure and a possible obstruction causes liver fibrosis. In maternity, obstruction of hepatic veins could happen as a result of stenosis or thrombosis. Variceal bleeding is the most deadly problem in pregnancy with co-existing Budd-Chiari syndrome, with 29.4per cent incidence of abortion and 33.3% perinatal death. The goal of this situation autochthonous hepatitis e report would be to present the management of non-cirrhotic variceal bleeding in expecting mothers with Budd-Chiari syndrome in the early 2nd trimester. We report a pregnant feminine at 13-14 weeks gestation introduced into the hospital with profuse hematemesis. Doppler ultrasonography (USG) ended up being utilized to confirm the diagnosis of Budd-Chiari syndrome-hepatic vein occlusion enter maternity. Abdominal USG revealed hepatomegaly with hepatic veins dilation, while endoscopy revealed grade IV esophageal varices and grade IV gastric varices. Laboratory results indicated disseminated intravascular coagulation due to hemorrhage. The patient was handed rigid liquid resuscitation and three stuffed red cells transfusion to stabilize the hemodynamic. Bleeding had been successfully handled by intravenous octreotide, tranexamic acid, and supplement K. The case shows that the handling of non-cirrhotic variceal bleeding in pregnancy with Budd-Chiari problem requires a multidisciplinary approach and regular fetal tracking to make certain optimal outcomes.Prolonged real and mental health changes, known as post-COVID problems (PCC), could impair the quality-of-life (QoL) of healthcare employees. The purpose of this study was to determine elements that subscribe to cognitive impairments and QoL among COVID-19 survivors working as medical employees. This cross-sectional research included healthcare employees at Prof. Dr. Chairuddin P. Lubis Universitas Sumatera Utara Hospital, Medan, Indonesia. The Montreal Cognitive Assessment (MoCA) was made use of to assess the cognitive function, while the World Health Organization Quality-of-Life simple Version (WHOQOL-BREF) survey ended up being used to evaluate the QoL. Factors related to cognitive and QoL condition had been examined utilizing Mann-Whitney and Chi-squared tests.