Hsiu-Chi Cheng, MD, PhD: Institute of Clinical Medicine, Departme

Hsiu-Chi Cheng, MD, PhD: Institute of Clinical Medicine, Department of Internal Medicine, Medical College, National Cheng Kung University, Tainan, Taiwan. Wei-Lun Chang, MD: Institute of Clinical Medicine, Department of Internal Medicine, Medical College, National Cheng Kung University, CP-868596 mw Tainan, Taiwan. Bor-Shyang Sheu, MD: Department of Internal Medicine, Institute

of Clinical Medicine, Institute of Basic Medical Sciences, Medical College, National Cheng Kung University, Tainan, Taiwan. Acknowledgements Financial support : This work was supported by grants from the National Scientific Council (NSC982314B006036), the Department of Health (DOH99-TD-C-111-003), and the National Health Research Institute (NHRI-EX99-9908BI), Taiwan References 1. Suriani R, Colozza M, Cardesi E, Mazzucco D, Marino M, Grosso S, Sanseverinati S, Venturini I, Borghi A, selleck screening library Zeneroli ML: CagA and VacA Helicobacter pylori antibodies in gastric cancer. Can J Gastroenterol 2008, 22:255–258.PubMed 2. Wada Y, Ito M, Takata S, Tanaka S, Yoshihara M, Chayama K: Relationship between Helicobacter pylori tyrosine-phosphorylated CagA-related markers and the development

of diffuse-type gastric cancers: a case-control study. Digestion 2010, 82:10–17.PubMedCrossRef 3. Martin Guerrero JM, Hergueta Delgado P, Esteban Carretero J, Romero Castro R, Pellicer Bautista FJ, Herrerias Gutierrez JM: Clinical relevance of Helicobacter pylori Fludarabine in vivo BCKDHA CagA-positive strains: gastroduodenal peptic lesions marker. Rev Esp Enferm Dig 2000, 92:160–173.PubMed 4. Salehi Z, Jelodar MH, Rassa M, Ahaki M, Mollasalehi H, Mashayekhi F: Helicobacter pylori cagA status and peptic ulcer disease in Iran. Dig Dis Sci 2009, 54:608–613.PubMedCrossRef 5. Hatakeyama M, Higashi H: Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis. Cancer Sci 2005, 96:835–843.PubMedCrossRef 6. Cendron L, Couturier M, Angelini A, Barison N, Stein M, Zanotti G: The Helicobacter pylori CagD (HP0545, Cag24) protein is essential for CagA translocation and maximal induction of interleukin-8 secretion. J Mol Biol

2009, 386:204–217.PubMedCrossRef 7. Lee IO, Kim JH, Choi YJ, Pillinger MH, Kim SY, Blaser MJ, Lee YC: Helicobacter pylori CagA phosphorylation status determines the gp130-activated SHP2/ERK and JAK/STAT signal transduction pathways in gastric epithelial cells. J Biol Chem 2010, 285:16042–1650.PubMedCrossRef 8. Argent RH, Kidd M, Owen RJ, Thomas RJ, Limb MC, Atherton JC: Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori. Gastroenterology 2004, 127:514–523.PubMedCrossRef 9. Wiedemann T, Loell E, Mueller S, Stoeckelhuber M, Stolte M, Haas R, Rieder G: Helicobacter pylori cag-Pathogenicity island-dependent early immunological response triggers later precancerous gastric changes in Mongolian gerbils. PLoS One 2009, 4:e4754.PubMedCrossRef 10.

Comments are closed.