Drug release profiles (in pH 7.4 phosphate buffer) show that the new drug loading technique gives

controlled release during a period of about 7 days at 37 degrees C. By contrast, gel spheres loaded with sodium diclofenac using the conventional diffusion technique produced almost total release of the drug within about 24 h. The thermal stability of sodium diclofenac, the PEG/AMPS-co-NIPA AZD2171 SIPN, and the prodrugs made with the SIPN and sodium diclofenac was studied. A near zero-order release kinetics was found in the in vitro release of sodium diclofenac with in situ loading PEG SIPN prodrug. We have, for the first time, studied sodium diclofenac release behavior from the PEG SIPN hydrogel systems. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 113: 2217-2231, 2009″
“We study the effect of the depolarization field on a domain wall structure near the surface of a ferroelectric. Since in real situation bound and screening charges

form an electric double layer, Belinostat inhibitor the breaking of this layer by the domain wall induces stray depolarization field, which in turn changes the domain wall structure. Power law decay of the stray field results in the power law of polarization saturation near the surface, as compared to exponential saturation in the bulk. Obtained results predict that the surface broadening of ferroelectric domain walls appeared near Curie temperature as well as describe domain wall depth profile in weak ferroelectrics. We qualitatively describe extra-broad domain walls near LiNbO3 and LiTaO3 surfaces observed experimentally at room temperature, SN-38 which probably originate at high temperatures but did not fully relax their width with temperature decrease allowing for lattice

pinning and defect centers. Thus results have broad implication for fundamental issues such as maximal information storage density in ferroelectric data storage, domain wall pinning mechanisms at surfaces and interfaces, and nucleation dynamics. (C) 2009 American Institute of Physics. [doi: 10.1063/1.3236644]“
“A nano-composite coating was formed using nano-ZnO as pigment in different concentrations, to a specially developed alkyd-based waterborne coating. The nano-ZnO modified composite coatings were applied on mild steel substrate by dipping. The dispersion of nano-ZnO particles in coating system was investigated by scanning electron microscopic and atomic force microscopic techniques. The effect of the addition of these nanopigments on the electrochemical behavior of the coating was investigated in 3.5% NaCl solution, using electrochemical impedance spectroscopy. Coating modified with higher concentration of nano-ZnO particles showed comparatively better performance as was evident from the pore resistance (R(po)) and coating capacitance (C(c)) values after 30 days of exposure.