Combination therapy with mdm2 and efgr inhibitors

Provided is a method of treating a proliferative disease, condition, or disorder in a subject by administering a combination of an inhibitor of p53 and MDM2 binding and an EGFR inhibitor. Various embodiments of the disclosed methods provide a synergistic anti-proliferative or anti-apoptotic effect compared to administration of one agent alone….

Source: http://www.freshpatents.com/-dt20120621ptan20120156197.php

DPP-4 Peptidase-4 Dipeptidy

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