Boehringer Ingelheim had no

role in study design and analysis. SHORT AND LONG TERM BIOLOGICAL VARIATION OF HIGH SENSITIVITY TROPONIN T (HS-TNT) AND N-TERMINAL B-TYPE NATRIURETIC PEPTIDE (NT-PROBNP) IN THE STABLE DIALYSIS POPULATION M Fahim, A Hayen, A Coburn, G Dimeski, D Johnson, J Craig, A Rita Horvath, S Campbell, C Hawley MF received unrestricted Everolimus in vitro research support from Roche Diagnostics and Fresenius Medical Care THE DEVELOPMENT AND GROWTH OF CKD.QLD: A FOUR YEAR JOURNEY S Krishna Venuthurupalli, A Salisbury, W E Hoy, H G Healy, R G Fassett, A Salisbury SV is completing his PhD via CKD.QLD which is supported by Amgen, NHMRC Australia (Australian Fellowship: Hoy), the Colonial Foundation of Australia, Queensland Health (in kind) and Roche. URINARY CLUSTERIN EPZ015666 in vitro PREDICTS GRAFT RECOVERY WITHIN FOUR HOURS OF KIDNEY TRANSPLANTATION T Pianta, P Peake, N Buckley, M Kelleher, J Pickering, Z Endre TP acknowledges

the financial support of the Jacquot Research Entry Scholarship and a University of New South Wales Australian Postgraduate Award. ZE has received research and travel support from Alere and Abbott. “
“Rapid diagnosis and initiation of the treatment on congenital obstructive nephropathy are important for young children to slow down renal injury. The aim of our study was to investigate the role of urinary extracellular matrix metalloproteinase inducer (Emmprin), matrix metalloproteinase 9 (MMP-9) and tissue inhibitor of metalloproteinase 1 (TIMP-1) in the long-term from follow-up of children with ureteropelvic junction (UPJ) narrowing on conservative treatment. The study included 40 children with non-obstructed hydronephrosis

due to unilateral UPJ narrowing who were treated conservatively and followed up for 24 months. Voided urine samples were collected at diagnosis and at 3, 9, 15 and 24 months of follow-up, respectively. Three enzymes concentrations were measured in urine. During the follow-up, 25 children showed renal function stabilization (non-obstructed group) and 15 children renal function deterioration (obstructed group). In non-obstructed group, a comparison between urine 3 enzymes levels at the last follow-up and at baseline showed no significant differences (all P>0.05). Glomerular filtration rate (GFR) and split renal function (SRF) showed the similar trends. In obstructed group, a comparison between the 3 enzymes levels at diagnosis and at basal condition showed a significant increase (all P<0.01). But GFR and SRF showed a marked reduction at diagnosis (all P<0.001). Receiver operator characteristic (ROC) analyses revealed a better diagnostic profile for uEmmprin, uMMP-9 and uTIMP-1 in identifying children with abnormal SRF (<40%) at 24 months of follow-up [Area under the curve (AUC) 0.877, 0.727 and 0.