As an important study limitation we have to say that we only compared two groups in the present study: an experimental group and a control group. Given a large placebo response in several samples, it could be that our results are only the consequences of a placebo effect. Thus, future studies should also add a placebo group to the experimental design. To compare the effectiveness of the wingwave method to CBT for example, researchers could further add another group which gets an intervention with the CBT. A comparison of EMDR and CBT in the treatment of PD was Inhibitors,research,lifescience,medical already done by Faretta (2012) and the results showed that both treatments Inhibitors,research,lifescience,medical are effective

for the resolution of a PD. However, EMDR treatment seems to have a faster progress in symptom reduction which is maintained over time. Another comparison could be conducted between EMDR and wingwave in the treatment of anxiety and analyses can potentially show if the wingwave method is

an improved alternative to EMDR. Sirtuin inhibitor Furthermore, future research could Inhibitors,research,lifescience,medical check, if there are time-dependent effects of the method. In the present study, participants received an intervention with the wingwave method 2 weeks after the first time of measurement and another 2 weeks later, participants completed the second time of measurement. Thus, it may be interesting to find out how stable the present results are over a longer period of time. To the best of our knowledge, the present study was the first one to investigate the effects of the wingwave method in reducing anxiety. The results from this pilot study seem promising Inhibitors,research,lifescience,medical to help people in the future to decrease rapidly their anxiety. We hope that this study will help to inform and motivate future research to further investigate this new method in the treatment

of anxiety. Conflict of Interest None declared.
The Inhibitors,research,lifescience,medical earliest studies of the corpus callosum (cc), the largest neural pathway connecting the two cerebral only hemisperes (Innocenti 1986), date back to 16th century. Considered for many centuries as the “seat of the soul” (Manzoni 1998), it took until the 18th century for Franz Joseph Gall and Johann Spurzheim to dissect alcohol-fixed brains and describe bundles of axons passing through the white matter and connecting the two hemispheres (Manzoni 2011). The cc is made up of myelinated and unmyelinated axons and glial cells (Innocenti 1986). Callosal axons originate from pyramidal neurons located in layers II/III and V of the cerebral cortex (Innocenti 1986) and use glutamate as neurotransmitter (Barbaresi et al. 1987), released in the cc by unmyelinated fibers at specific axon–glia synaptic junctions (Ziskin et al. 2007).