65 mm). The mean induced corneal

astigmatism was significantly less in the MICS group than in the SICS group (P <=.0495) 1 week postoperatively and subsequently. The averaged difference map on videokeratography showed focal corneal flattening corresponding to the incision and coupled steepening around the flattened area 2 days postoperatively in both groups. The flattening and steepening gradually reduced to virtually the preoperative shape by 8 weeks; the changes were significantly less in the MICS group than in the SICS group. Of the irregular astigmatic components, JPH203 datasheet higher-order irregularity was significantly less in the MICS group than in the SICS group up to 2 weeks postoperatively

(P <=.0470).

CONCLUSION: Induced astigmatism, CA3 focal wound-related flattening of the peripheral cornea, and corneal surface irregularity were signficantly less after coaxial MICS than after SICS.”
“The evolution of organ transplantation has produced results so successful that many transplant programs commonly see recipients with medical risks, which in the past, would have prohibited transplantation. The Eighth Annual American Society of Transplant Surgeons State-of-the-Art Winter Symposium focused on the high-risk recipient. The assessment of risk has evolved over time, as transplantation has matured. The acceptance of risk associated with a given candidate today is often made in consideration

of the relative value of the organ to other candidates, the regulatory environment, and philosophical notions of utility, equity, and fairness. In addition, transplant programs must balance outcomes, transplant volume, and the costs of organ transplantation, which are impacted by high-risk recipients. Discussion focused on various types of high-risk recipients, such as those with coronary artery disease, morbid obesity, and hepatitis C; strategies to reduce risk, such as down-staging of hepatocellular carcinoma and treatment of pulmonary hypertension; the development of alternatives to transplantation; and the degree to which risk can or should be used to de. ne candidate selection. These approaches can modify the impact of recipient risk on transplant outcomes and permit transplantation to be applied successfully DAPT concentration to a greater variety of patients.”
“Objective Happiness is a central component in quality of life but little is known about its meanings among people living with an advanced disease and those from diverse communities. This study explores and compares, for the first time, the centrality and interpretations of happiness across two cultural groups living with advanced cancer. Methods Semi-structured interviews among 26 Black Caribbean and 19 White British cancer patients were conducted in hospital and home settings.