05), but there was no significant differences exsist between pre treatment and post treatment in SAP patients (P > 0.05). Conclusion: CRP probably will predict the prognosis and the severity of patients with SAP early, and can be used as the prognosis 3-deazaneplanocin A index at the same time. It is worth to popularized and applicated. Key Word(s): 1. Acute pancreatitis; 2. C reactive protein; 3. Diagnostic value; 4. prognosis; Presenting Author: ZHAOBAO MIN Additional Authors: GUBING QUAN, LING XIAO, CHEN XI Corresponding

Author: ZHAOBAO MIN Affiliations: The Fourth Military Medical University; The Fourth Military Medical University Objective: To investigate the effect of genistein derived from soybean on rats with acute pancreatitis. Methods: 45 SD rats were randomly divided into 3 groups: three groups adopt arginine (2-amino-5-guanidinovaleric acid) acute pancreatitis model was induced by intraperitoneal injection, RXDX-106 order Control group were intragastric administration through the mouth in 100 g/kg soybean protein three times every day; Model groups were intragastric administration by in 2 ml in normal saline; Genistein groups was given 5, 7, 4′-triatomic isoflavone intragastric administration through the mouth in 100 mg/kg. Observation rat survival and death within 72 h of situation; Detecting survival rats 24 h, 48 h, 72 h of serum amylase levels, pancreatic tissue pathological index score

is calculated. Results: Soybean protein group 6 h mortality rates is highest at 53%; Three hydroxyl groups of isoflavones 6 h cumulative mortality rate is only 6.7%, to 24 h for peak mortality (33.3%), compared with soybean protein group was significantly delayed, mortality in both groups had significant difference (p < 0.01). Three hydroxyl groups of isoflavones survival rats 24 h, 48 h, 72 h serum amylase activity was significantly lower than soybean protein group (1830 + 325 vs. 2667 + 262 U/L, p < 0.01), (1744 + 321 vs. 2935 + 301 U/L, p < 0.01), (1319 + 338 vs.

2725 + 235 U/L, p < 0.05). Conclusion: Through stomach perfusion genistein can delay the peak of death of rats with acute pancreatitis, improve the survival rate of rats, and inhibit the serum pancreatic amylase activity, probably by reduce pancreatic inflammation and play an important role. Key Word(s): 1. MCE公司 Acute pancreatitis; 2. Genistein; 3. Soybean protein; 4. Rats; Presenting Author: LI HONG-YU Additional Authors: ZHANG NINGNING, LIU XU, LIU WEI-WEI, ZHANG YAN-LIN, GUO XIAO-ZHONG Corresponding Author: GUO XIAO-ZHONG Affiliations: General Hospital of Shenyang Military Area Command Objective: To investigate the reasons why serum amylase did not drop in the patients with mild acute pancreatitis, and provide reference for prevention and treatment of mild acute pancreatitis. Methods: The clinical data of 307 cases with mild acute pancreatitis in our hospital were retrospectively analyzed.