The main data collected were: age, sex, indication for intraosseous FAK inhibitor access, localisation of insertion, success rate, drugs and fluids administered, and complications. All published studies concerning

the EZ-IO device were systematically searched and reviewed for comparison.

Results: Fifty-eight patients representing 60 EZ-IO procedures were included. Mean age was 47 years (range 0.5-91), and the success rate was 90%. The main indications were cardiorespiratory arrest (74%), major trauma (12%), and shock (5%). The anterior tibia was the main route. The main drugs administered were adrenaline (epinephrine), atropine and amiodarone. No complications were reported. We identified 30 heterogeneous studies representing 1603 EZ-IO insertions. The patients’ characteristics and success rate were similar to our study. Complications were reported in 13 cases (1.3%).

Conclusion: The EZ-IO provides an effective way to achieve vascular access in the pre-hospital setting. Our results were similar to the cumulative results of all studies involving the use of the EZ-IO, and that

can be used for comparison for further studies. (C) 2012 Elsevier Ireland Ltd. All rights reserved.”
“BACKGROUND: Emerging data suggest that pregnancy conveys high risk for severe complications from the 2009 pandemic influenza A virus (2009 H1N1) infection.

CASE: We describe an infected pregnant woman with critical illness owing to acute respiratory distress syndrome despite previous vaccination. Early serologic testing indicated absent immunity, followed Angiogenesis inhibitor 11 days later by a robust immune response.

The patient required mechanical ventilation for 11 days, but ultimately improved, and was discharged home on hospital day 14.

CONCLUSION: With the expectation that 2009 H1N1 will continue to cause disease in the immediate future, the virus has been included as a component of the 2010-2011 seasonal influenza vaccine. Vaccination of pregnant women is strongly encouraged. However, regardless of vaccination history, clinicians should remain vigilant for 2009 H1N1 infection when the virus is in circulation, selleck compound and should not delay antiviral treatment of pregnant women with suspected influenza. (Obstet Gynecol 2011; 117: 470-2) DOI: 10.1097/AOG.0b013e3181fd2e38″
“Despite a more physiological morphology of atrial anastomosis in the bicaval technique with respect to standard biatrial anastomosis in orthotopic heart transplantation (OHT), the impact on the long-term outcome is still not clear. In this retrospective study, we sought to investigate the morphology and function of the atria through magnetic resonance imaging (MRI) and transthoracic echocardiography (TIE). Moreover, we aimed to analyse the accuracy of TIE with respect to MRI.