While technological advances in capacity for sequencing analysis have exceeded the benchmark measure of computing

power, Moore’s Law, there is no doubt that this success has been largely tied to computational advances. The transfer of this knowledge from the laboratory to the health care setting faces a steep climb to establish Pacritinib phase 3 information management practices in the US. Improved clinical knowledge from research is highly dependent on recovering standardized, useful clinical information from medical practice. The delivery of knowledge in clinically useful formats to support decision-making processes is similarly critical. The information management needs to Inhibitors,research,lifescience,medical span these gaps is found in the electronic health information technology (health IT). The major components of a health IT system to support personalized Inhibitors,research,lifescience,medical medicine includes widely used electronic medical record systems and personal health records that consumers can use for recording their own health care information. A second component is a nationwide effort to enable health information exchange among health care providers Inhibitors,research,lifescience,medical and institutions that will enable portability of information to suit purposes on demand. A third element

includes electronic decision support capabilities that engage medical records systems to facilitate evidence-based health care choices by the health care provider. Collectively, these are dependent on data standards that Inhibitors,research,lifescience,medical enable semantic and syntactic interoperability of data across health IT systems. As a health care enterprise,

the US has a dearth of electronic information to support these needs, and it will take many years to achieve all of these steps to technical support benefit all patients. The inability to connect information sources is a major contributor to the high costs of clinical research, particularly clinical trials. Despite escalating health care costs and substantial service inefficiencies in the US, there has been little incentive until recently to make capital investments in information Inhibitors,research,lifescience,medical systems for the inpatient and ambulatory care setting. Brefeldin_A Today, less than 20% of all physicians use electronic health record systems, and far fewer have systems that provide decision support capabilities to aid personalized medicine. Some progress is being made on the requirement for electronic transmission of prescriptions from the health care provider to the pharmacy. Computerized physician order entry (CPOE) for ordering laboratory tests and other services has also been improving. As part of the American Recovery and Reinvestment Act of 2009, nearly $20 billion will be invested in the next several years to build health IT capacity through network capabilities, support acquisition of electronic systems by practice groups and health care institutions, and provide fiscal incentives for adoption and use of health IT systems.